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EC number: 204-411-8
CAS number: 120-61-6
Recovery of radioactivity following dermal application
Total administered dose (%)
Single application (80 mg)
5 dose repeat application (80 mg/dose)
Skin – application site
Data from a radiotracer study in rats to determine the
absorption, distribution, and excretion of dimethyl
terephthalate (DMT) following dermal administration
demonstrate no evidence of skin irritation in rats after a
single or repeated dermal application of 80 mg of 14C-DMT.
Approximately 11% of the single dose and 13% of 5 repeated
doses were recovered from the urine and faeces within 10
days of initial dosing.
It was concluded that DMT is rapidly absorbed and excreted
by the body, and that no significant quantities accumulate
in the tissues.
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