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EC number: 204-411-8
CAS number: 120-61-6
No further remarks.
The acute intraperitoneal toxicity of DMT was investigated in the rat.
Dose levels of 3000, 3900, 5020 and 6590 mg/kg bw dimethyl terephthalate
(20% in corn oil) were administered intraperitoneally to male Long-Evans
rats (3-6 per group). All deaths occurred within 48 hours of injection.
Symptoms were slight to moderate weakness at all dose levels, and slight
tremors and some ataxia at the two highest doses (5020 and 6590 mg/kg
bw). Except for peritoneal irritation with foreign body reaction on the
surface of the abdominal viscera, no morphologic evidence of gross or
microscopic abnormalities was seen in the organ systems of the DMT
treated animals. The acute intraperitoneal LD50 of dimethyl
terephthalate in rats was found to be 3900 mg/kg bw under the conditions
of this study.
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