Registration Dossier

Physical & Chemical properties

pH

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Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP, non-guideline study, limitations in design and/or reporting but otherwise adequate for assessment.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Principles of method if other than guideline:
pH-metry
potentiometry for acid reserve

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): TFA
- Lot/batch No.: SFA1006230

Results and discussion

pH value
pH value:
0.45
Concentration:
10 other: %m/m
Remarks on result:
other: aqueous solution

Any other information on results incl. tables

Acid reserve = 35.0 g NaOH / 100 g sample

Applicant's summary and conclusion

Conclusions:
TFA is of high acidity.
The information is relevant for corrosivity assessment and waiving of acute toxicity tests on animals.
Executive summary:

The acidity of Trifluoroacetic acid (TFA) was estimated by pH and acid reserve measurements. No experimental data were provided. Results are respectively 0.45 for a 10% aqueous solution, and 35g NaOH/100g.