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EC number: 200-929-3
CAS number: 76-05-1
In aqueous solution, the pH of the substance is naturally low
(pH<4) and for testing on organisms either the sodium salt (NaTFA) or pH
adjustment were required.
Environmental official classification according to Annex VI of
Regulation (EC) No 1272/2008 of the European Parliament and of the
Council of 16 December 2008: Trifluoroacetic acid is reported under the
Index No 607-091-00-1 and is classified as Aquatic Chronic 3, H412.
This official classification is conservative because, based on the key
studies available, the substance should not be classified for the
environment as explained below :
Short-term E/LC50 values are available for algae (key study growth rate
72hEC50 = 237 mg/L), daphnia (48hEC50 > 100 mg/L) and fish (96hLC50 >
100 mg/L). All of the key studies demonstrate E/LC50 above 100 mg/L,
showing that the substance does not need to be classified for acute
toxicity to aquatic organisms according to the CLP and the UN-GHS
Additionally, trifluoroacetic acid is not readily biodegradable and due
to the log Kow < 4 there is no tendency to bioaccumulate. Chronic
toxicity data are available for algae showing a 72hErC10 of 5.6 mg/L and
for daphnia showing a 21dNOEC above 25 mg/L. Therefore, the substance
does not need to be classified for chronic toxicity to aquatic organisms
according to the CLP and UN-GHS criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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