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EC number: 701-124-4
CAS number: -
The test substance 4,4'-MDI/TPG was slightly irritating when tested on male and female rabbits under occlusive conditions. 24 hours after application slight erythema and very slight to slight edema were observed. All effects were fully reversible within 7 days.
Even the test results indicate only a slightly irritating effect, reversible within 7 days, the MDI group approach is followed and a worst-case approach is adopted in which the most bioaccessible substances are read across to all substances of the MDI category. Therefore, the harmonized CLP classification as skin irritant category 2 (H315) for 4,4’-MDI is adopted for all category substances, including the substance 4,4’-MDI-TPG.
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