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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Desmodur PF is not readily biodegradable. After 28 days 0 % of the test substance had been degraded in a modified MITI Test (according to OECD Guideline 301 C) (Currenta 2010a)
For PMDI, 0% biodegradation was found in a test carried out according to OECD Guideline 302C (Caspers et al, 1986).

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

No biological biodegradation can occur as the hydrolysis rate is very rapid.

One biodegradation screening test in water is available for PMDI. According to OECD Guideline 302C (Inherent biodegradability: Modified MITI Test (II)) 0% biodegradation was found after 28 days based on oxygen consumption under aerobic condtions with domestic sewage (adaptation not specified). Another test according to OECD guideline 301 C showed no biodegradation within 28 days.

PMDI hydrolyses very rapidly in water. Hence, this test measured the biodegradation of the hydrolysis products of pMDI. Based on the justification in the category approach, it is assumed that all MDI analogues included in the category are not readily biodegradable.