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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

No toxicity observed in a short-term study with Daphnia magna at loadings up to 1000 mg/L (and this value may be considered for the derivation of a PNECaqua value). In this study the test substance was stirred in water in the usual way prior to exposure to the daphnids.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1 000 mg/L

Additional information

In one experiment the PMDI was dispersed into water by high speed shearing (24,000 rpm) instead of the usual stirring. This gave a 24h EC50 of 129.7mg/L which was almost certainly due to the significantly increased production of 4,4'-methylenedianiline (MDA), a substance which is known to be relatively toxic to daphnids. It may be considered that the 24h EC50 of 129.7 mg/L is irrelevent because the dispersing method used in this one experiment does not reflect a situation that might occur in the real environment.

The result of the short-term toxicity test (EC50 >1000 mg/L) (Caspers et al, 1986) was corroborated with the long-term mecocosm studies (Heimbach, 1993) where no effects were seen on zooplankton at loadings up to 10,000mg/L.