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Short-term toxicity to aquatic invertebrates

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Description of key information

No toxicity observed in a short-term study with Daphnia magna at loadings up to 1000 mg/L (and this value may be considered for the derivation of a PNECaqua value). In this study the test substance was stirred in water in the usual way prior to exposure to the daphnids.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1 000 mg/L

Additional information

In one experiment the PMDI was dispersed into water by high speed shearing (24,000 rpm) instead of the usual stirring. This gave a 24h EC50 of 129.7mg/L which was almost certainly due to the significantly increased production of 4,4'-methylenedianiline (MDA), a substance which is known to be relatively toxic to daphnids. It may be considered that the 24h EC50 of 129.7 mg/L is irrelevent because the dispersing method used in this one experiment does not reflect a situation that might occur in the real environment.

The result of the short-term toxicity test (EC50 >1000 mg/L) (Caspers et al, 1986) was corroborated with the long-term mecocosm studies (Heimbach, 1993) where no effects were seen on zooplankton at loadings up to 10,000mg/L.

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