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Toxicity to microorganisms

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Description of key information

A static test according to ISO 8192 -1986/B "Activated sludge respiration inhibition" was investigated. After 3 hours Desmodur PF showed 12.3 % respiration inhibition of activated sludge at the highest test item concentration of 10000 mg/L. (Bayer, 1989)
One OECD 209 Activated Sludge, Respiration Inhibition Test is available for PMDI. Based on the respiration rate using activated sludge, the 3h EC50 was found to be >100mg/L (Caspers et al, 1986).

Key value for chemical safety assessment

EC50 for microorganisms:
10 000 mg/L

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