Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

PMDI reacts readily with water to form predominantly insoluble and inert polyurea (Yakabe et al 1994) and therefore long-term tests are not appropriate for the derivation of PNEC values.
In a study with Daphnia magna (Caspers et al, 1986) no long-term toxicity was observed after 21d exposure to 10mg/L. The test was carried out according to OECD Guideline 211 and the result was corroborated by the mesocosm study where no chronic effects were seen to the zooplankton at 1000 and 10,000 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
10 mg/L

Additional information

PMDI is rapidly hydrolysed in aqueous solution. However, PMDI is hydrophobic and poorly soluble in water and thus the heterogeneous reaction with water or soil is less rapid. The major product of such a reaction is insoluble polyurea.

In the production of PMDI the formation of insoluble polyurea would cause abrasion problems and blockage of valves and pipes and therefore releases of PMDI to effluents are expected to be non-existent. Since production is performed in closed systems, releases to soil and sediment are also expected to be negligible.

Categories Display