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EC number: 221-066-9
CAS number: 2996-92-1
In accordance with REACH Annex XI, Section 3, exposure of terrestrial
organisms to trimethoxyphenylsilane is not significant (RCR << 1) and
the substance has a low hazard potential based on the available acute
In accordance with Annex XI, Section 3, exposure of terrestrial
organisms to trimethoxyphenylsilane is not significant.
Furthermore, the hazard assessment based on acute aquatic toxicity data
shows no toxicity toward aquatic organisms of all three trophic levels
(all acute effect values, i.e. E(L)C50s were > 100 mg/L). The substance
is well soluble and thus, greater toxicity in long-term tests is
Even though no hazard was identified in acute aquatic studies, PNECs
were derived for the purpose of risk characterization, using the
threshold value of 100 mg/L in combination with standard safety factors
as outlined in ECHA guidance R.10. As the substance hydrolyses rapidly,
the environmental hazard assessment, PNEC derivation and risk
characterization is based on the silanol hydrolysis product following a
worst case approach. The other hydrolysis product, methanol, is known
for its absence of environmental toxicity. The risk characterization for
the silanol hydrolysis product indicated no risk to the aquatic
environment (RCR < < 1).
For detailed information on the risk assessment please see the attached
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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