Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-066-9
CAS number: 2996-92-1
Trimethoxyphenylsilane (CAS No. 2996 -92 -1) hydrolyses rapidly in
contact with water (DT50 = 0.4 h, OECD 111) to phenylsilanetriol (CAS
No. 3047 -74 -3) and methanol (CAS No. 67 -56 -1). The
ECHA guidance R.16 states that “for substances where hydrolytic DT50 is
less than 12 h, environmental effects are likely to be attributed to the
hydrolysis product rather than to the parent itself” (ECHA, 2016). The
ECHA guidance R.16 also suggests that in cases where the hydrolysis
half-life is less than 12 h, the breakdown products, rather than the
parent substance, should be evaluated for aquatic toxicity. Thus, the
environmental fate assessment in this dossier is based on the hydrolysis
products phenylsilanetriol and methanol.
characterized by a high, estimated water solubility of 1.0E+06
mg/l at 20°C (QSAR) and a low potential for volatilization from water (Henry's
Law Constant = 4.0 E-09 Pa m3mol-1at
12°C and estimated vapour pressure = 5.3E-05 Pa at 25°C).
There is no evidence for any significant biodegradation. However, its
potential for bioaccumulation and its affinity to soil and sediment is
low based on its low log Kow (-0.021 at pH 7, OECD 107) and its
estimated log Koc (1, QSAR), respectively.
The main target
compartment of environmental methanol is air (73%) and water (16%) based
on fugacity model calculations. Methanol is miscible with water at 20
°C, does not undergo hydrolysis and volatilization is not a significant
removal process from the aquatic compartment (HLC = 0.461 Pa m3/mol, VP
= 128 hPa). However, methanol is readily biodegradable and has a low
potential for bioaccumulation (log Kow = -0.74). Its toxicity toward
aquatic organisms is low, with acute toxicity values of well above 1000
mg/L. Overall, methanol is considered to have a low environmental hazard
Source: OECD SIDS
Initial Assessment Profile, SIAM, 2004
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again