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EC number: 221-066-9
CAS number: 2996-92-1
A long-term toxicity study to aquatic invertebrates is not necessary as
- exposure considerations in accordance with Annex XI, Section 3,
indicate that the exposure of aquatic organisms to
trimethoxyphenylsilane is absent or not significant
- the substance has a low hazard potential based on the available
In accordance with Annex XI, Section 3, exposure of aquatic
organisms to trimethoxyphenylsilane (CAS No. 2996-92-1) is absent or not
The environmental hazard assessment, PNEC derivation and risk
characterization is based on the silanol hydrolysis product,
phenylsilanetriol, as the substance hydrolyses rapidly. The other
hydrolysis product, methanol, is known for its absence of environmental
The hazard assessment showed no short-term aquatic hazard to all
three trophic levels (all acute effect values > 100 mg/L). Consequently,
no PNECs aqua (freshwater/marine water) were derived. The silanol
hydrolysis product is well soluble. Significant deviations from this
overall ecotoxicity profile are not expected and greater long-term
toxicity in an additional test with aquatic invertebrates is considered
However, for the purpose of exposure-based adaptation as in the
present endpoint, PNECs were derived in the Chemical Safety Report (CSR,
Chapters 9 and 10) for the required risk characterization even though no
hazard was identified in the available aquatic toxicity studies. The
PNECs aqua (freshwater/marine water) were derived using a worst-case
threshold value of 100 mg/L in combination with the standard assessment
factors of 1000 and 10000, respectively, as outlined in ECHA guidance
The risk characterization for the silanol hydrolysis product of
the substance indicated no risk to the aquatic environment (RCR < < 1).
For detailed information on the risk assessment please refer to
the attached documentation in Section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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