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EC number: 221-066-9
CAS number: 2996-92-1
Table 1. Results of analysis of test media (measured as
Table 2. Test results
Table 1. Results of analysis of test media
Nominal concentration (mg/L)
Mean measured concentration (mg/L)
Mean measured concentration as percentage of nominal
0 (Solvent control)
*The limit of quantification (LOQ) of the analytical method was 0.00017
Mean percentage immobilisation after 24 hours
Mean percentage immobilisation after 48 hours
observed immobilization was isolated to replicate C and is likely due to
contaminated glassware. Since no immobilization was observed in the
remaining three replicates of the control, the solvent Control or the
treatment level tested, this immobilization was not considered to have
impacted the interpretation of the exposure.
EC50 (48 h) > 100 mg/L (nominal, D. magna, OECD 202)
It is likely that the test organisms were predominantly exposed to the
hydrolysis products of the test substance.
One experimental study for the short-term
toxicity of trimethoxyphenylsilane to aquatic invertebrates is
available, in which an EC50 (48 h) value of > 0.20 mg/L and a NOEC (48
h) of ≥ 0.20 mg/L were determined for the effects on the mobility of Daphnia
magna (OECD Guideline 202 (Daphnia sp. Acute Immobilisation
Test, Springborn Smithers 2008).
The results are expressed relative to nominal
test substance concentration. The corresponding mean measured
concentration of the substance in the treated test medium over the
course of the test was 0.0029 mg/L. However, the maximum concentration
tested in the study (0.2 mg/L) is lower than the prediced solubility of
the substance (1700 mg/L). Therefore, it was considered appropriate to
read across from the structurally analogous substance, trichloro(phenyl)
silane (98-13-5) as both substances hydrolyse rapidly to
In the read-across source study, no
effects were observed to Daphnia magna at the highest
concentration tested of 100 mg/L (OECD Guideline 202 (Daphnia sp.
Acute Immobilisation Test, Springborn Smithers 2009).
As the substance is subject to rapid
hydrolysis, it is therefore likely that the test organisms were
primarily exposed to hydrolysis products retained in the test media.
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