Registration Dossier
Registration Dossier
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EC number: 210-323-0 | CAS number: 612-83-9
Endpoint summary
Administrative data
Description of key information
Additional information
In the key study, 3,3´-dichlorobenzidine was tested for "ready biodegradablilty" in a sound and sufficiently well documented study (relibility score 2, reliable with restrictions) according to the OECD-guideline 301 A (AFNOR method) with deviations especially regarding substance concentration (lower, because of the poor water solubility) and analytics (spectroscopic monitoring of substance concentration). The study results, constituted by the single results of serveral different laboratories taking part, demonstrate that 3,3´-dichlororbenzidine is not readily biodegradable under the applied conditions (0% degradation at the end of the observation period).
Results showing a certain degree of decrease in spectral absorbance under modified experimental conditions (presence of yeast extract as a nutriant source) are interpreated by the authors as inherent biodegradability. However, as demonstrated by radioactive labelling in another published study (Appleton), this decrease in spectroscopic absorption is most probably caused by the strong adsorption of 3,3´-dichlorobenzidine to organic matter. As organic matter is increasing rapidly especially in presence of yeast extract as external carbon source, an ever increasing fraction of test substance is adsorbed to organic matter and thus pelleted before spectroscopic detection.
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