5,5-dimethylhydantoin

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Testing was conducted between 26 October 2009 and 19 November 2009.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

EXAMPLE:

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 19-08-2008 Date of Signature: 04-09-2009

Type of method:

other: EXAMPLE: Differential scanning calorimetry (DSC)

Test material

Test material information

Constituent 1

Reference substance name:

DMH

IUPAC Name:

DMH

Details on test material:

Sponsor's identification: DMH
Description: white crystalline solid
Batch number: N5439431
Date received: 24 February 2006
Storage conditions: room temperature in the dark

Results and discussion

Melting / freezing point

Melting / freezing pt.:

449 K

Remarks on result:

other: air (static)

Any other information on results incl. tables

Results

Thermograms and thermographic data for Determinations 1 and 2 are shown in Figure 4.1. and Figure 4.2. and in the following tables respectively.

Figure 4.1  Thermogram – Determination 1 (Please see attached Fig 4.1 & 4.2 Thermogram – Determination)

Table 4.2           Thermographic Data – Determination 1

Thermal Event	Interpretation	Temperature
		ºC	K
Endotherm	Melting Temperature	176.10	449

 

Figure4.2 

 Thermogram – Determination 2 (Please see attached Fig 4.1 & 4.2 Thermogram – Determination)

Table4.3           Thermographic Data – Determination 2

Thermal Event	Interpretation	Temperature
		ºC	K
Endotherm	Melting Temperature	176.14	449

 

Mean melting temperature: 449 ± 0.5 K

Applicant's summary and conclusion

Conclusions:

The melting/freezing temperature of the test material has been determined to be 449 ± 0.5 K.

Executive summary:

Method

The determination was carried out by differential scanning calorimetry (DSC) using the procedure specified in ASTM E537-86, Method A1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008.

Conclusion

The melting/freezing temperature of the test material has been determined to be 449 ± 0.5 K.