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EC number: 402-170-5
CAS number: 106359-91-5
C.I. REACTIVE YELLOW 174; GIALLO REATTIVO 174; JAUNE REACTIF 174; REAKTIV GELB 174
In a GLP-compliant skin irritation study, performed according to OECD guideline 404, FAT 40224/C (moistened, 0.5g) was applied, semi-occlusive, to the skin of three New Zealand White rabbits for 4 hours. After 4 hours, the treated skin was flushed with water and observations were made for an additional 72 hours. The test substance showed a primary irritation score (24,48,72 hours) of 0.0 and local signs (mean 1 hour to 72 hours) consisted of grade 0.00 erythema and grade 0.0 edema. In the area of application, an orange staining of the treated skin by pigment or coloring of the test article was observed. No corrosive effect was evident on the skin. Under the conditions of this experiment, the test substance was found to be not irritating or corrosive to rabbit skin.
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