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Long-term toxicity to aquatic invertebrates

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Description of key information

The lowest estimated freshwater invertebrate 21-day NOELR (Lowest Observed Effect Loading Rate) value is 4.888 mg/l based on reproduction, for hexane.

Key value for chemical safety assessment

Additional information

The aquatic toxicity was estimated using the Petrotox computer model, which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism. The estimated freshwater invertebrate 21-day NOELR (Lowest Observed Effect Loading Rate) value is 4.888 mg/l based on reproduction, for hexane.