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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

The estimated freshwater fish 28-day NOELR (Lowest Observed Effect Loading Rate) value is 2.8 mg/l based on growth, for n-hexane.

Key value for chemical safety assessment

Additional information

The aquatic toxicity was estimated using the Petrotox computer model (v. 3.04), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism. The estimated freshwater fish 28-day NOELR (Lowest Observed Effect Loading Rate) value is 2.8 mg/l based on growth, for hexane.