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EC number: 239-290-0
CAS number: 15245-44-0
Experiments were conducted to measure the GI absorption and elimination
of a single oral dose of lead-210 acetate in infant and adult rhesus
monkeys. Urinary and fecal excretion of absorbed lead were examined for
23 days post-exposure. Infant monkeys eliminated less and absorbed more
of the administered lead. Adult animals excreted more absorbed lead in
feces, whereas urinary excretion was similar between adults and infants.
Increased absorption of administered lead and reduced fecal excretion of
absorbed lead resulted in a greater body burden of lead in infant
animals compared to adults. Blood lead concentrations were inversely
correlated with body burden and percent absorption of ingested lead.
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