Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-747-8
CAS number: 2224-33-1
One male rat was given a single dose of 550 mg/kg bw of the test
substance by oral gavage. The animal showed no adverse effects within 3
days of dosing and appeared healthy. A second fastened male was dosed
with 2000 mg/kg bw and also showed no adverse effects within 3 days of
dosing and appeared healthy. A third male rat was dosed with 2000 mg/kg
bw and showed adverse effects which were fully reversible within 3 days.
Another rat was dosed with 2000 mg/kg bw and also showed adverse
effects, which were reversible within 3 days.
An acute oral toxicity test was performed according to OECD 425 and GLP
on butan-2-one O,O',O''-(vinylsilanetriyl)oxime. No mortality was
observed and the LD50 was determined to be >2000 mg/kg bw in rats.Two
of three rats showed transient adverse clinical signs which were
no longer evident on day 3.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
За да гарантираме, че се възползвате максимално от функциите на нашия уебсайт, сме въвели „бисквитки“.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again