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EC number: 218-747-8
CAS number: 2224-33-1
1: Incidence of dermal response to challenge dosing.
Vehicle (propylene glycol)
Dinitrochlorobenzene (no details given)
100% no details given
Skin reactions were graded:
0 no reaction
1 scattered mild redness
2 moderate and diffuse redness
3 intense redness and swelling
* 5 animals had eschar and 2 had
**1 animal had eschar
A guinea-pig maximisation test conducted with GLP but limited in some
respects reported a response to challenge (using 50% test substance) in
14 of 15 animals at 24 and 48 h. Responses in 1 of 3 and 0 of 3 were
reported at 24 and 48 hours, respectively, in the small negative control
group. A response of 30% or more in an adjuvant test indicates
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