Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 236-675-5
CAS number: 13463-67-7
Data are available for the effect of different upgraded ilmenite (UGI, >80% TiO2) slags on survival and reproduction of the terrestrial arthropod Folsomia candida. Conservatively, a long-term NOEC of 1000 mg/kg dw and a chronic LOEC of 3000 mg/kg dw is derived based on observed effects. In sum, TiO2 appears to have a low potential for toxicity to soil arthropods.
Data are available for the effect of different upgraded ilmenite
slags (UGI, >80% TiO2) on survival and reproduction of the terrestrial
arthropod Folsomia candida. Conservatively, a long-term NOEC of 1000
mg/kg dw and a chronic LOEC of 3000 mg/kg dw is derived. Upgraded
ilmenites (UGI) consist primarily (> 80%) of titanate, i.e., TiO2 with
Fe, Al, Si, Mg and other metals, and are poorly soluble and not
biodegradable. The transformation/dissolution of three UGI products at
loadings of up to 100 mg/L over 24 h did not result in any significant
release of titanium (Skeaff, 2007). Bulk and nano-TiO2 forms are also
poorly soluble in environmental media (Brouwers, 2009; Klawonn, 2017
a-f). Based on similarity in composition and the same poor solubility of
UGI and TiO2, read-across of ecotoxicological data from UGI to TiO2 is
One supporting study on the acute toxicity of microsized TiO2 to
Porcellio scaber is available and indicates that microsized TiO2 has a
low toxic potential to terrestrial arthropods: Jemec et al. (2016)
performed two non-standardized leaves-consumption tests, in which adult
animals of both sexes of Porcellio scaber were offered two pieces of the
same hazelnut leave either individually or in groups of 10 organisms for
14 d. Both pieces were either treated with deionized water (controls) or
one piece was treated with deionized water and the other piece was
treated with a suspension of micro-sized aluminium-zirconium coated TiO2
(1000 mg/kg dw leave). Consumption of control and treated leaves did not
significantly differ (unbounded 14 d NOEC ≥ 1000 mg/kg dw leave,
nominal), indicating that isopods neither avoided nor selected TiO2
treated leaves after 14 d of exposure to both treatments. Exposure
occurred via food and not via the soil. Therefore, the results of this
test are considered supporting data.
Furthermore, one supporting study on the acute toxicity of
nanosized TiO2 to Porcellio scaber, is available. In this study,
sonicated and non-sonicated dispersions of a nano-sized TiO2 material
(15 nm, anatase) applied to dry leaves did not affect weight change,
feeding rate, food assimilation efficiency, and survival of Porcellio
scaber after 3 days of dietary exposure in a non-standardized test.
Derived 3 d NOEC values were 3000 mg/kg diet dw. Furthermore,
inconsistent dose-response relationships were observed for antioxidant
enzyme activities at these effect levels. Exposure occurred via the food
and not via the soil. Therefore, the results of this test are not
considered for hazard assessment.
In sum, nano- and microsized TiO2 appears to have a low potential
for toxicity to soil arthropods based on data available for springtails
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again