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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Fish: Iwan GR et al (1975) exposed Fathead minnow (Pimephales promelas) to C12-14 AO under static conditions for 96 hours. The LC50 (96 h) based on nominal concentrations of amine oxide ranged from 2.67 to 3.46 mg AO/L depending on the source and pH of the water used.

In a full life-cycle toxicity test (similar to EPA OPPTS 850.1500) fathead minnows (Pimephales promelas) were exposed to C12 -14 AO for 302 days under flow through conditions [Aquatic Environmental Services (1976) ]. The NOEC was 0.42 mg AO/L (mean measured concentration), based on reduced fry survival, reduced egg hatch, and occluded eyes in test fish.

Daphnia: The acute immobilisation (EC50) of C12-14 AO to Daphnia magna was determined according to OECD TG 202 and EC method C.2 under static conditions over a duration of 48 h [Noack M (2001)]. The 48 h EC50 value, based on nominal test concentrations, was 3.1 mg AO/L

A 21-day survival and reproduction test with Daphnia magna following OECD TG 211 is available for C12-14 AO [Maki (1997)]. The 21 -day NOEC was 0.70 mg AO/L, based on both survival and reproduction.

Algae: Ginkel & Kroon (1990) exposed Pseudokirchnerella subcapitata to C12-14 AO under static conditions for 72 hours according to OECD TG 201. The ErC50 (72 h) was 0.266 mg AO/L. The ErC50 (72 h) based on the geometric mean of the four studies available with this species is 0.143 mg AO/L

The toxicity of C12-14 AO to algae was evaluated in a 28 -day freshwater periphyton microcosm assay [Belanger (1999)]. The No-Observed Effect Concentration (NOEC) of the substance to the periphyton community was determined to be >67 ug AO/L, the highest test concentration evaluated (mean measured concentration).

Microorganisms: Kolvenbach (1990) exposed Pseudomonas putida to C12 -14 AO for 18 hours in a Bringmann-Kohn test. The EC10, based on reduction in growth rate, was 24 mg AO/L.

Sediment-dwelling organisms: No studies are available, however risk characterisation using the equilibrium partitioning method indicates that the risk to sediment dwelling organisms is adequately controlled and there is no need for further refinement of the assessment through testing.