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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 9 - June 07, 2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well reported study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2002
Report Date:
2002

Materials and methods

Principles of method if other than guideline:
A saturated solution of 1 g of C12-14 amine oxide in 20 mL n-octanol was stirred for 24 hours at room temperature followed by centrifugation at 2500 rpm to separate the undissolved solids from the aqueous phase. An aliquot of the n-octanol phase was evaporated till dryness under an airflow at 70 deg C. The resulting dry residue was then dissolved in deionised water. The concentration of amine oxide in the resolubilised residue was quantified using 2 methods: DBAS and nitrogen determination.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): GTS02902

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
n-octanol
Solubility:
33.9 g/L

Applicant's summary and conclusion