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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 931-292-6 | CAS number: 308062-28-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is manufactured and supplied as an aqueous solution. For the purposes of compliance, attempts were made to freeze dry a sample of the substance so that some of the applicable physico-chemical testing could be completed. NMR and IR were used to confirm that the freeze drying process had not degraded the substance immediately after drying. However, water solubility and partition coefficient, gave unexpected results. Further analytical work subsequently confirmed that the dry substance had degraded to some extent, forming the free amine. This reduced the reliability of studies performed using the freeze-dried substance, namely relative density, surface tension, water solubility, log Kow and flammability.
The substance is a highly hygroscopic white solid with a melting point expected to be in the range of 126 -136 °C, based on the melting points of the pure alkyl dimethylamine oxide (AO) constituents. Aliphatic amine oxides undergo thermal decomposition/Cope elimination between 110 -200 °C. The relative density of the substance is approximately 0.716. The vapour pressure is estimated to be between 1.6E-06 and 7.5E-05 Pa, based on the estimated vapour pressures of the individual AO constituents. The substance is surface active with a surface tension of 34.1 mN/m at 20ºC. The dissociation constant is 4.01. The substance is predicted to be non-explosive based on chemical structure and oxygen balance of the AO constituents and non-oxidising, based on chemical structure. The substance is non-flammable.
The log Kow is < 2.7. This value is considered to be conservative as it is based on the measured value for solubility in n-octanol and the CMC values for the C12 and C14 homologues. For comparison, a log Kow of -1.08 is derived from the measured n-octanol solubility of 33.9 g/L and the measured water solubility of 409.5 g/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.