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EC number: 224-320-7
CAS number: 4306-88-1
study was performed to assess the acute oral toxicity of the test
material in the Sprague-Dawley CD strain rat. The method followed that
in the OECD Guideline for Testing Chemicals No. 401 "Acute Oral
Toxicity" (adopted 24 February 1987) and Method B1 of Commission
Directive 92169/EEC (which vonstitutes Annex V of Council Directive
results may be used as a basis for classification and labelling under
Annex VI of Council Directive 67/548/EEC (as adapted to technical
progress by Commission Directive 93/21/EEC) relating to the
classification, packaging and labelling of dangerous substances.
a range-finding study, a group of ten fasted animals (five males and
five females) was given a single oral dose of undiluted test material at
a dose level of 2000 mg/kg bodyweight. The animals were observed for
fourteen days after the day of dosing and were then killed and subjected
to gross pathological examination. There
were no deaths. No signs of systemic toxicity were noted during the
showed expected bodyweight gain during the study. No
abnormalities were noted at necropsy.
acute oral median lethal dose (LD50) of the test material in the
Sprague-Dawley CD-strain rat was found to be greater than 2000 mg/kg
bodyweight. No symbol and risk phrase are required according to EU
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