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EC number: 224-320-7
CAS number: 4306-88-1
study was performed to assess the irritancy potential of the test
material to the skin of the New Zealand White rabbit. The method used
followed the recommendations of the OECD Guidelines for Testing of
Chemicals No. 404 "Acute Dermal Irritation/Corrosion" (adopted 17 July
1992) and Method B4 of Commission Directive 92/69/EEC (which constitutes
Annex V of Council Directive 67/548/EEC).
results may be used as a basis for classification and labelling under Regulation
No. 1272/2008 (CLP).
single 4-hour, semi-occluded application of the test material to the
intact skin of three rabbits produced well-defined erythema and very
slight to slight oedema. Desquamation and crust formation were also
test material produced a primary irritation index of 3.5 and was
classified as a moderate irritant to rabbit skin according to the Draize
classification scheme. No corrosive effects were noted.
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