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EC number: 222-720-6
CAS number: 3586-55-8
The test substance causes serious damage to
the eye and was scored positive for skin irritation.
The test was performed according to OECD
guideline 404. Three New Zealand rabbits were used; 0.5 ml of the
undiluted test substance were applied to the skin; semiocclusive, 4 h
exposure; post exposure observation period 15 days. The average score
(24-72h) for erythema and edema was 1.2 and 1.3 respectively. The
effects for edema was not fully reversible after 15 d.
Cornea Serious damage, not reversible
Iris Score 1 but scoring not possible at
Redness Highest scores observed at several
Chemosis Highest scores observed at several
Discharge Highest scores observed at several
readings, not reversible
In a test according to OECD guideline 405
the eye irritating portential of the test item was determined. 0.1 mL of
the undiluted test substance was instilled into the conjunctival sac of
one female rabbit. Readings were performed at 1, 24, 48, 72 h, 7 days,
14 days, 21 days, and 28 days after instillation. The test substance
causes serious damage to the eye which was not reversible.
Classification, Labeling, and
Packaging Regulation (EC) No 1272/2008
The available experimental test data
are reliable and suitable for classification purposes under Regulation
(EC) No 1272/2008. Based on these data, the substance is considered to
be classified for skin irritation (Cat. 2, H315) and eye damage (Cat. 1, H318)
under Regulation (EC) No 1272/2008, as amended for the tenth time in
Regulation (EC) No 2017/776.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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