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Partition coefficient

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Endpoint:
partition coefficient
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
The hydrolysis studies demonstrate that the test substance "reaction product ethylene glycol and para-formaldehyde” hydrolyses rapidly and completely. Therefore, data from the hydrolysis products are regarded sufficient to fulfill the data requirements.
Reason / purpose:
read-across source
Key result
Type:
log Pow
Partition coefficient:
-1.36
Remarks on result:
other: No data on temperature and pH.
Endpoint:
partition coefficient
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
The hydrolysis studies demonstrate that the test substance "reaction product ethylene glycol and para-formaldehyde” hydrolyses rapidly and completely. Therefore, data from the hydrolysis products are regarded sufficient to fulfill the data requirements.
Reason / purpose:
read-across source
Key result
Type:
log Pow
Partition coefficient:
0.35
Temp.:
25 °C
Remarks on result:
other: No more information available

Description of key information

The study to determine the partition coefficient does not need to be conducted because the substance decomposes. The hydrolysis study demonstrates that the commercial product hydrolyses rapidly and completely. This behavior applies equally to the test substance "reaction product ethylene glycol and para-formaldehyde”. The n octanol/water partition method requires that the test substance remain intact in the aqueous phase. Based on the properties of the test substance, the study is technically not feasible. Therefore, the partition coefficients of the hydrolyses products were considered. The log Pow of the hydrolyses products were determined to be 0.35 for formaldehyde and -1.36 for ethylene glycol.

Key value for chemical safety assessment

Additional information

Information on formaldehyd:

For the degradation product formaldehyde a log Kow of 0.35 has been obtained.