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EC number: 203-907-1
CAS number: 111-78-4
no further remarks
To test the acute skin irritant effect the test item was applied to the
shaven dorsal skin of 3 female and 3 male rabbits. The product was
administered undiluted and the time of exposure in the patch test was 4
hours. The dermal reactions were fully reversible within 20 days.
According to the study, the test item 1,5-Cyclooctadiene showed slightly
irritant effect on the skin of male and female rabbits.
no further results
The test item was investigated for irritant effects on the eye and
associated mucous membranes of 3 female and 3 male rabbits according to
OECD TG 405 (1981). The test substance was applied in a single dose of
0.1 ml into the conjuntival sac of each animal. According to the study,
the test item showed no irritant effect on the eyes and mucosa of male
and female rabbits.
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