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EC number: 203-907-1
CAS number: 111-78-4
no further results
Three groups of 6 male rats each were exposed nose-only for a single, 4
hour period to vapors of the test item in air at chamber vapor
concentrations of 1400, 2700 or 4300 ppm. Mortality was 0/6, 1/6 and 4/6
at 1400, 2700 and 4300 ppm respectively. By 3 hours into the exposure
all rats failed to respond to external sound stimuli. At the end of
exposure, the 2 rats at 4300 ppm and 4 rats at 2700 ppm were immobile.
Threee rats at 1400 ppm exhibited ataxia. Other clinical signs of
toxicity observed after exposure: ocular discharge,
lethargy, irregular respiration. Ocular discharge,
ruffled fur or stained perineum were observed up
to 4 days following exposure.
On an acute inhaltion basis, test item is considered slightly toxic.
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