2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol

Endpoint summary

Additional information

In accordance with Annex IX, column 2 of Regulation (EC) No. 1907/2006, toxicity testing to terrestrial organisms does not need to be conducted as the Chemical Safety Assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate a need for further investigations. Environmental exposure from manufacturing and all uses at industrial sites is considered to be negligible. There is no release to the water compartment since manufacturing and all industrial uses are dry processes and no wastewater is generated during the processes. Moreover, a direct release to soil is not expected since the surfaces at industrial settings are sealed preventing any release to soil. The release to air is assumed to be 0 % since the substance is removed from the exhaust stream by scrubbing and gas incineration during use. As a consequence indirect exposure of the environmental compartments surface water, sediment and soil via the atmospheric compartment is considered to be negligible. This is confirmed by very low predicted environmental concentrations (PEC).
Additionally, two uses by professional workers are reported. During use the substance reacts to completion with a second reactant with expected low release to the environment. After reaction the substance is no longer present in the article and no release to the environmental compartments is anticipated. A release to the air with subsequent deposition to other environmental compartments during reaction is expected to be low based on the low vapour pressure of the substance. Assumed direct releases of 0 - 0.5 % to soil and 1 % to water reflect the very low overall release to the substance. Consequently, the predicted environmental concentrations (PEC) arising from these two uses are very low.The calculated PECs were compared to the corresponding PNEC values as part of the environmental risk assessment. All risk characterization ratios (RCR) were clearly below 1 indicating no risk for all environmental compartments (please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).Thus, toxicity studies with terrestrial organisms are not deemed necessary.