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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Description of key information

stable in N, N-Dimethylformamide (DMF)
stable in Ethanol/Kolliphor HS15/Tap water 1/4/5

Additional information

The stability in organic solvents was evaluated by determining any loss of the test substance during test period. HPLC-MS method was used as quantification method. 10 mg/mL und 50 mg/mL formulations of the test item in DMF are homogeneous and stable for at least 4 days at room temperature. The 5 mg/mL and 200 mg/mL formulations of the test item in Ethanol/Kolliphor HS15/Tap water 1/4/5 were homogeneous and stable for at least 48 hours at room temperature.