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EC number: 205-597-3
CAS number: 143-28-2
The percentage absorbance of dose 14C-cetyl alcohol
(hexadecan-1-ol) = ca 1%. At least 65% of the absorbed dose is excreted
as carbon dioxide in the expired air.
When tested diluted in solvent vehicles, the degree of absorption was
influenced by the concentration and the type of solvent that was used.
For n-cetyl alcohol in squalene, approximately 2% of the applied dose
was absorbed at the 0.5%, reducing with increased concentration to 1% of
the applied dose at 5%.
For n-cetyl alcohol in castor oil and in TEC (triethyl citrate),
slightly less was absorbed at the applied concentrations of 0.5 and 5%
Of a dose of 5% 1-14C-cetyl alcohol applied to the skin of nude mice for
24 hours, 1% was absorbed.
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