Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-517-7
CAS number: 141-98-0
An acute oral study in rats was performed according to OECD Guideline 425 (Acute Oral Toxicity: Up-and-Down Procedure). Different number of rats in four dose groups were administered with the test substance in sesame oil as follows: 181 mg/kg bw. : 5 rats, 568 mg/kg bw. : 5 rats, 1809 mg/kg bw. : 1 rat, 2067 mg/kg bw. : 1 rat. Mortality was observed in the 568 (4/5), 1809 (1/1), 2067 (1/1) mg/kg bw dose groups. In the 181 mg/kg bw dose group ataxia, reduced muscle tone and dyspnoea in all 5 of 5 animals were observed. In gross pathology, no signs or abnormalities were observed. All surviving animals gained the expected body weight. Based on the study results a LD50 of 568 mg/kg bw of 568 mg/kg bw was determined. Consequently, the test substance is classified for acute oral toxicity Cat. 4, H302 according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again