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EC number: 205-517-7
CAS number: 141-98-0
A Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test was performed on rats via orally administered with 30, 100, 300 mg/kg bw/day of the test substance according to OECD Guideline 422. NOAEL values determined for F0 generation, reproductive toxicity as well as for development of F1 offspring: 30 mg/kg bw/day.
Toxicity to reproduction test was done with OECD Guideline 422. Crl:CD rats were exposed to test item for 28days. test item was given by oral gavage once a daily. For parental animals clinical signs, mortality and body weight changes were observed. NOAEL is determined to be 31 mg/kg bw/day. For pups viability, mortality and body weight changes were observed. LOAEL is determined to be 31mg/kg bw/day.
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