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PBT assessment

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PBT assessment: overall result

Reference
Name:
(Z)-2-butene-1,4-diol (B2D)
Type of composition:
legal entity composition of the substance
State / form:
liquid
Reference substance:
(Z)-2-butene-1,4-diol (B2D)
PBT status:
the substance is not PBT / vPvB
Justification:

Not P/vP because the substance is readily biodegradable. Not B/vB because log Kow <1 (-0.9). Substance is T because it is classified as Specific Target Organ Toxicity - Repeated Exposure (STOT-RE), Category 2 under Annex VI of Regulation (EC) 1272/2008, based on systemic effects observed at 60 mg/kg in the OECD 422 study in rats.