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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

No key study for fish is available for guaiacol, but a weight of evidence approach can be applied.

Key value for chemical safety assessment

Additional information

No reliable study is available on guaiacol for fish: two data are from secondary literature (primary data not available) and gave on Perca sp. LC50 48H = 70 -80 mg/l (Little, 1970) and LC50 96H = 44 mg/l (unknown species, Gilron et al., 1999). These data can however be used in a weight of evidence approach together with data obtained on a structural analogue of guaiacol, the paramethoxyphenol (isomer in para position), for which two studies quoted in reliability 2 are available. These studies gave a LC50 96H of 28.5 mg/l on Oncorhynchus mykiss (Hodson et al., 1984) and a LC50 96H = 110 mg/l on Pimephales promelas (Geiger et al., 1985). All these data indicate that guaiacol can be considered as harmful for fish.