Guaiacol

Henry's Law constant

Administrative data

Endpoint:

Henry's law constant

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

Comparison of headspace and gas-stripping methods for determining the Henry's law constant (H) for organic compounds of low to intermediate H

Author:

Sagebiel J.C., Seiber J.N. and Woodrow J.E

Year:

1992

Bibliographic source:

Chemosphere, 25: 1763-1768

Materials and methods

Principles of method if other than guideline:

No data

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Guaiacol

EC Number:

201-964-7

EC Name:

Guaiacol

Cas Number:

90-05-1

Molecular formula:

C7H8O2

IUPAC Name:

Phenol

Details on test material:

Guaiacol was obtained from Aldrich Chemical Co.
Reported purities were 99%, and it was used without further cleanup.

Results and discussion

Henry's Law constant H

H:

0.11 Pa m³/mol

Temp.:

25 °C

Applicant's summary and conclusion

Executive summary:

Guaiacol solution (1000 ppm) was placed in a headspace vial, sealed, thermostated and then pressurized to ca. 179 kPa gauge. The vapour was sampled and analysed by gas chromatography. The Henry's law constant measured was 0.11 Pa.m3/mole at 25°C.