Registration Dossier

Administrative data

Endpoint:
sediment toxicity: short-term
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No sufficient information was available to evaluate the validity of this study. No information was available about the test substance and the test conditions.

Data source

Reference
Reference Type:
publication
Title:
Effect of chlorinated phenol derivatives on various cell models
Author:
Cernakova M.
Year:
1994
Bibliographic source:
Folia Microbiol, 39(4): 315-320

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
It was prepared at the Department of Wood, Pulp and Paper, Faculty of Chemical Technology, Slovak Technical University, Bratislava.

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
yes

Test organisms

Test organisms (species):
Tubifex tubifex

Study design

Study type:
other: no data
Test type:
not specified
Water media type:
not specified
Type of sediment:
not specified
Exposure duration
Duration:
45 min
Exposure phase:
total exposure duration

Test conditions

Details on test conditions:
The test substance was diluted in 1.4-dioxane at a concentration of 0.1 g/L. The test substance was evaluated versus the unaffected control, control with 1.4-dioxane, and the positive control represented by benzo[a]pyrene.
No complementary information was available about the test condition and the test design.
Reference substance (positive control):
yes
Remarks:
benzo[a]pyrene

Results and discussion

Effect concentrationsopen allclose all
Duration:
25 min
Dose descriptor:
LD50
Effect conc.:
100 mg/L
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
45 min
Dose descriptor:
LD100
Effect conc.:
100 mg/L
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
No mortality was observed in the control with 1.4-dioxane and in the control uninfluenced.

Applicant's summary and conclusion