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EC number: 250-284-7 | CAS number: 30674-80-7
The PBT Assessment for 2-isocyanatoethyl methacrylate is based on the criteria set out in the "Guideline on information requirements and chemical safety assessment, Chapter R. 11: PBT Assessment" (ECHA 2008).
For 2-isocyanatoethyl methacrylate a study on "readily biodegradability" according to OECD 301 B and the EU-Method C.4 -C
2-isocyanatoethyl methacrylate as well as its hydrolysis products have log Kow values below 3. Thus, the test substance does not meet the screening criterion for bioaccumulation and is not considered to be bioaccumulative (B) or very bioaccumulative (vB).
Testing of 2-isocyanatoethyl methacrylate on algae (Scenedesmus subspicatus) according to the OECD-Guideline 201 resulted in a NOEC of 97.4 mg/L (mean measured, geometric mean).
Moreover, 2-isocyanatoethyl methacrylate is not classified for STOT RE (Cat 1 or 2), carcinogenicity, mutagenicity or reproductive and developmental toxicity in mammals. Thus the criteria set out in Annex XIII of Regulation (EC) No. 1907/2006 are not met and not considered to meet the T criterion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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