Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted on 1 September 1981
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
according to
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
static method
GLP compliance:
Type of method:
static method
Specific details on test material used for the study:
- Appearance: Colorless to light yellow liquid- Storage conditions: Room temperature in the dark, under nitrogen
Key result
20 °C
Vapour pressure:
18 Pa
Remarks on result:
other: extrapolated value
25 °C
Vapour pressure:
27 Pa
Remarks on result:
other: extrapolated value

Antoine Formula of test item:


Log P = 7.73674 + 2135.48 / (t +228.326)


P : Vapor pressure of MOI [mmHg]

t : Temperature [°C]


By this formula, we obtained the vapor pressure at 20°C, 25°C.



27 Pa at 298.15K (25 °C), 18 Pa at 293.15K (20 °C), using a static method.


Description of key information

18 Pa at 20°C (OECD 104, static method)        

OECD 104 with static method

OECD 104 with static method

OECD 104 with static method

OECD 104 with static method

Key value for chemical safety assessment

Vapour pressure:
18 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the substance 2-isocyanatoethyl methacrylate (CAS 30674-80-7) 18 Pa at 20 °C was determined according to OECD 104 with static method (2016, study no. MOI-20160407). The extrapolated result 23.3 Pa at 20 °C from thermogravimetric analysis (2012, study no. MOI-20120308) supports the value of the static method. The QSAR result 14.5 Pa at 20 °C with (SPARC v4.6) assists the experimental values.