Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.097 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.974 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.01 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
2 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
1.33 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.133 mg/kg sediment dw

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.209 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Classification related key information

Biodegradation in water: screening test: 87% (DOC) in 28 days (OECD 301B and EU Method C.4-C)

Log Kow: 1.72 (KOWWIN v.1.68) for 2 -isocyanathoethyl methacrylate

Acute toxicity:

- to Fish: LC50 (96 h) = 162 mg/L (nominal) for Pimephales promelas (OECD 203)

- to Crustacea: EC50 (48 h) > 113 mg/L (mean measured) for Daphnia magna (OECD 202)

- to Algae: ECr50 (72 h) > 97.4 mg/L (mean measured) for Pseudokirchneriella subcapitata (OECD 201)

Chronic toxicity:

- to Fish: not available

- to Crustacea: not available

- to Algae: NOEC (72h) = 97.4 mg/L (mean measured) for Pseudokirchneriella subcapitata (OECD 201)

 

Classification justification according to CLP

Based on the data above, 2-isocyanatoethyl methacrylate is considered to be readily biodegradable. The acute aquatic toxicity L(E)C50 is > 1 mg/L for fish, invertebrates and algae. Valid chronic toxicity data are available for the alga Pseudokirchneriella subcapitata with a NOEC > 10 mg/L. 2-isocyanatoethyl methacrylate does not need to be classified according to the Regulation (EC) No. 1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2ndATP).

 

Classification justification according to DSD

Based on the data above, 2-isocyanatoethyl methacrylate is considered to have no potential for accumulation (log Pow < 3) and is rapidly degradable. The acute aquatic toxicity L(E)C50 is > 10 mg/L for all trophic levels. Therefore 2 -isocyanatoethyl methacrylate does not need to be classified according to the Directive 67/548/EEC.