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Administrative data

Endpoint:
Henry's law constant
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable calculation method using measured physical chemical properties.

Data source

Reference
Reference Type:
other: REACH Guidance
Title:
Chapter R.16: Environmental Exposure Estimation
Author:
European Chemicals Agency
Year:
2009
Bibliographic source:
Guidance on Information, Requirements, and Chemical Safety Assessment
Report date:
2009

Materials and methods

Principles of method if other than guideline:
Calculated using physico-chemico properties in CSR section 1.3 using EQUATION R.16-4 (HENRY = (VP*MW/Solubility) in the REACH guidance R.16.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
420-640-8
EC Name:
-
Cas Number:
138495-42-8
Molecular formula:
C5H2F10
IUPAC Name:
420-640-8

Results and discussion

Henry's Law constant Hopen allclose all
H:
49 600 Pa m³/mol
H:
other: This value indicates that the test substance would readily volatilize from water and is unlikely to repartition to water.

Applicant's summary and conclusion

Conclusions:
Calculated HLC of 4.96E4 Pa*m3/mol indicates the test substance would readily volatilize from water and is unlikely to repartition to water.
Executive summary:

A Henry's Law constant of 4.96E4 Pa*m3/mol was calculated for the test substance from measured vapour pressure (24800 Pa) and solubility (126 mg/L) values and molecular weight (252.05 g/mol) using EQUATION R.16-4 (Henry = (VP*MW)/Solubility) in the REACH guidance R.16. This value indicates that the test substance would readily volatilize from water and is unlikely to repartition to water.

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