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EC number: 420-640-8 | CAS number: 138495-42-8
Table 1: Individual Animal Ocular Effects
The test substance was evaluated for acute eye irritation potential in 3 young adult New Zealand white rabbits. An aliquot of approximately 0.1 mL of the test substance was administered to 1 eye of each animal. The eyes remained unwashed following treatment. The untreated eye served as a control. The conjunctiva, iris, and cornea of each treated eye were evaluated and scored according to a numerical scale approximately 1, 24, 48, and 72 hours following administration. Under the conditions of the study, the test substance produced conjunctival redness in 1 rabbit. Mean values were calculated from the quantitative evaluation of ocular lesions observed in all rabbits at 24, 48, and 72 hours following administration. The overall conjunctival chemosis, conjunctival redness, iritis, and corneal opacity scores were 0, 0.11, 0, and 0, respectively.
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