Registration Dossier

Toxicological information

Health surveillance data

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Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2005

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Type of population:
general

Results and discussion

Applicant's summary and conclusion

Conclusions:
Reproductive toxicity:
Stillbirth or abortion, microcephaly, hydrocephaly, nasal hypoplasia, bone anomalies, growth retardation (human, dose level 2.5 - 12.5 mg/day ≅ 0.03 – 0.2 mg/kg bw/day).
LOAEL: 0.015 mg/kg bw/day