Registration Dossier

Administrative data

Endpoint:
adsorption / desorption
Type of information:
experimental study
Adequacy of study:
supporting study

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009
Report Date:
2009
Reference Type:
secondary source
Title:
Unnamed
Year:
1999

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.

GLP compliance:
yes
Media:
soil

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Soil type

Ka (=KF)

KaOC (=KFOC)

Kd (for 2nd desorption)

Silty clay loam

0.66

18

3.64

Sandy silt loam

8.51

247

8.56

Silty clay loam

0.65

42

3.44

clay loam

46.77

390

50.39

 

Kf 14.15, range 0.66 – 46.77, n=4

Koc 174, range 18 – 390, n=4

 

Warfarin adsorption strongly depends on pH and organic matter content. Adsorption increases with decreasing soil pH.

Applicant's summary and conclusion

Conclusions:
Kf 14.15, range 0.66 – 46.77, n=4
Koc 174, range 18 – 390, n=4

Warfarin adsorption strongly depends on pH and organic matter content. Adsorption increases with decreasing soil pH.