Registration Dossier
Registration Dossier
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EC number: 201-377-6 | CAS number: 81-81-2
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
- Principles of method if other than guideline:
- Method data are not available as the report details are unpublished.
- GLP compliance:
- yes
- Media:
- soil
Test material
- Reference substance name:
- Warfarin
- EC Number:
- 201-377-6
- EC Name:
- Warfarin
- Cas Number:
- 81-81-2
- Molecular formula:
- C19H16O4
- IUPAC Name:
- 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
Constituent 1
Results and discussion
Any other information on results incl. tables
Soil type |
Ka (=KF) |
KaOC (=KFOC) |
Kd (for 2nd desorption) |
Silty clay loam |
0.66 |
18 |
3.64 |
Sandy silt loam |
8.51 |
247 |
8.56 |
Silty clay loam |
0.65 |
42 |
3.44 |
clay loam |
46.77 |
390 |
50.39 |
Kf 14.15, range 0.66 – 46.77, n=4
Koc 174, range 18 – 390, n=4
Warfarin adsorption strongly depends on pH and organic matter content. Adsorption increases with decreasing soil pH.
Applicant's summary and conclusion
- Conclusions:
- Kf 14.15, range 0.66 – 46.77, n=4
Koc 174, range 18 – 390, n=4
Warfarin adsorption strongly depends on pH and organic matter content. Adsorption increases with decreasing soil pH.
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