Warfarin

Other distribution data

Administrative data

Endpoint:

other distribution data

Type of information:

experimental study

Adequacy of study:

supporting study

Data source

Reference

Reference 1

Reference Type:

review article or handbook

Title:

Unnamed

Year:

2009

Report date:

2009

Reference 2

Reference Type:

secondary source

Title:

Unnamed

Year:

1993

Materials and methods

Principles of method if other than guideline:

Method data are not available as the report details are unpublished.

GLP compliance:

yes

Type of study:

soil leaching

Test material

Test material information

Constituent 1

Reference substance name:

Warfarin

EC Number:

201-377-6

EC Name:

Warfarin

Cas Number:

81-81-2

Molecular formula:

C19H16O4

IUPAC Name:

4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

Results and discussion

Any other information on results incl. tables

It is noted that soils containing a low amount of organic matter and high pH, exhibited a moderate leaching potential when treated with a granular formulation of Warfarin. While under certain soil conditions (mainly alkaline soil types of low organic matter content) Warfarin may be more prone to leaching from the soil profile, the manner of use of Warfarin and the low rate of application mitigate against leaching to lower subsoil depths and ultimately to groundwater sources. it is noted that soils containing a low amount of organic matter and high pH, exhibited a moderate leaching potential when treated with a granular formulation of Warfarin. While under certain soil conditions (mainly alkaline soil types of low organic matter content) Warfarin may be more prone to leaching from the soil profile, the manner of use of Warfarin and the low rate of application mitigate against leaching to lower subsoil depths and ultimately to groundwater sources.