Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
supporting study

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009
Report Date:
2009
Reference Type:
secondary source
Title:
Unnamed
Year:
1990

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Route of exposure:
aqueous
Test type:
flow-through

Results and discussion

Bioaccumulation factor
Value:
<= 21.6 dimensionless

Any other information on results incl. tables

In the depuration phase the warfarin concentration decreased rapidly to levels at or below the detection limit so that after 11 days (the first day of warfarin measurement after termination of exposure) warfarin was no longer detectable in any of the test groups. Valid estimates of DT50 and DT90 can therefore not be provided. In conclusion DT90 ≤11 days.

Applicant's summary and conclusion