Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion
Type of information:
experimental study
Adequacy of study:
supporting study

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009
Report Date:
2009
Reference Type:
secondary source
Title:
Warfarin-induced necrosis of the skin
Author:
DeFranzo AJ, Marasco P, Argenta LC
Year:
1995
Bibliographic source:
Ann. Plast. Surg. 34, 203-208
Reference Type:
secondary source
Title:
Unnamed
Year:
1994

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.

GLP compliance:
yes
Remarks:
1994 is & 1995 is not GLP

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Test system

Type of coverage:
semiocclusive
Duration of treatment / exposure:
4 hour

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Time point:
other: 4 hour
Remarks on result:
other: non -irritant

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information